This NIH Funding Opportunity Announcement (FOA), supported by funds from the NIH Common Fund (Common Fund) and participating NIH Institute(s) and Center(s), invites applications from Institutions in African countries to develop an H3Africa Biorepository in order to provide an international site for the receipt, storage and distribution of samples from H3Africa research projects as well as other African research studies.
The NIH in partnership with the Wellcome Trust provide support for H3Africa, an initiative to enhance the development of sustainable research capacity in Africa that will use genomics as a part of a cutting-edge approach to promote health and combat disease.
Participating Organization(s): National Institutes of Health (NIH)
Funding Opportunity Title: Human Heredity and Health in Africa (H3Africa): H3Africa Biorepository Grants. (UH2/UH3)
Components of Participating Organizations:
This Funding Opportunity Announcement (FOA) is developed as a Common Fund initiative (http://commonfund.nih.gov/) through the NIH Office of the NIH Director, Office of Strategic Coordination (http://dpcpsi.nih.gov/osc/). The FOA will be administered by the National Human Genome Research Institute (NHGRI/NIH), (http://genome.gov) on behalf of the NIH.)
Activity Code UH2/UH3 Phase Innovation Awards Cooperative Agreement
Announcement Type Reissue of RFA-RM-12-003
Related Notices NOT-RM-12-026
Funding Opportunity Announcement (FOA) Number RFA-RM-12-008
Companion Funding Opportunity RFA-RM-12-006, U54 Human Heredity and Health in Africa (H3Africa): Collaborative Centers Cooperative Agreements
- · RFA-RM-12-007, U01 Human Heredity and Health in Africa (H3Africa) Research Projects Cooperative Agreements
- · RFA-RM-11-010, U41 Human Heredity and Health in Africa (H3Africa): Bioinformatics Network Cooperative Agreements
- · RFA-RM-12-005, U01 Human Heredity and Health in Africa (H3Africa): Ethical, Legal, and Societal Issues (ELSI) Research Program
Additional Information on Eligibility: Catalog of Federal Domestic Assistance (CFDA) Number(s) 93.310, 93.172
The purpose of this FOA is to call for applications for UH2/UH3 cooperative agreements that will provide funding to develop plans for an H3Africa Biorepository, building upon existing infrastructure. Applications should include plans for initial two-year UH2 Phase I studies (Phase I) as well as plans for an additional four years of support for implementing a full-scale H3Africa Biorepository (Phase II), beginning in 2014.
The outcome of the UH2 Phase I studies will be fully developed plans for a full-scale H3Africa Biorepository, with evidence that the challenges enumerated below have been overcome. Feasibility testing/planning activities should include testing proposed logistical approaches, training, developing collaborations and otherwise assembling or planning for additional infrastructure that will be needed for a full-scale bio-repository.
The outcome of the Phase II scale-up period will be a fully operational bio-repository that receives, processes, stores, and distributes samples for research in Africa, using state-of-the-art methods in accordance with international standards. Activities should include completion of infrastructure improvements, full-scale implementation of all study protocols and procedures for quality control/quality assurance, protection of human subjects and data/resource sharing, and collaboration with other H3Africa researchers.
Important Dates:
· Open Date (Earliest Submission Date) September 28, 2012
· Letter of Intent Due Date September 28, 2012
· Application Due Date(s) October 29, 2012, by 5:00 PM local time of applicant organization.
· AIDS Application Due Date(s) Not Applicable.
· Scientific Merit Review February/March, 2013
· Advisory Council Review May, 2013
· Earliest Start Date(s) August 1, 2013
· Expiration Date October 30, 2012
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